Under the guidance of interim manager Ruud van Nistelrooy, United finally achieved a breakthrough in the competition, following three consecutive draws under former manager Erik ten Hag.
Reflecting on the resounding win over City, Amorim admitted that this performance was "a dream way" to sign off. Yet, he emphasised that his approach at United would differ significantly.
United swiftly appointed Sporting Lisbon manager Ruben Amorim as his successor.
However, Manchester United, eager for an immediate replacement for the recently dismissed Erik ten Hag, issued an ultimatum: accept the job now or lose the opportunity. After careful consideration, Amorim ultimately chose to make the move.
Goals from Timo Werner and Pape Matar Sarr put the hosts in control in Round Four encounter in the capital.
Ole Gunnar Solskjaer's Manchester United were left to chase the game from the sixth minute when Neymar scored the opener.
Marcus Rashford grabbed all the limelights after coming off the bench and scoring thrice in a span of 18 minutes as Manchester United beat RB Leipzig 5-0.
Uruguay striker Cavani almost scored with his first touch after coming off the bench in the second half, but United were unable to break down Chelsea's well-drilled defence.
Marcus Rashford produced another late strike to sink Paris Saint-Germain as Manchester United beat last season's runners-up 2-1.
Cavani has won the Golden Boot in both Ligue 1 and Serie A, has scored 341 goals at club level since moving to Europe in 2007, including 35 in the UEFA Champions League.
