The latest US sanctions on Huawei threaten to devastate China’s first global tech competitor, escalating a feud with Beijing that could disrupt technology industries worldwide.

Huawei Technologies Ltd. is one of the biggest makers of smartphones and network equipment, but that 123 billion-a-year business is in jeopardy after Washington announced restrictions on use of American technology by foreign companies that make its processor chips.

The conflict is politically explosive because Huawei is more than just China’s most successful private company. It is a national champion among industries the ruling Communist Party is promoting in hopes of transforming China into a global competitor in profitable technologies.

The United States wants to kill Huawei, the official China Daily newspaper said Sunday.

On Monday, China’s Ministry of Commerce warned it will protect the legitimate rights and interests of Chinese enterprises, but gave no details of potential retaliation. Beijing has threatened in the past to issue an unreliable entities list that might restrict operations of American companies in China.

Friction over Huawei adds to a broader deterioration of US-Chinese relations.

The two sides have declared a truce in a trade war, but arguments over the origin of the coronavirus pandemic that is roiling the global economy have raised worries that agreement might fall apart.

Huawei is at the center of the US-Chinese conflict over Beijing’s technology ambitions, which Washington worries might erode American industrial leadership.

Huawei has few alternatives if Washington refuses to allow its suppliers to use US technology.

The company has developed some of its own chips but even the biggest non-US manufacturers such as Taiwanese giant TSMC need American components or production equipment.

Every electronics system that Huawei produces could be negatively impacted, said Jim Handy, semiconductor analyst for Objective Analysis, in an email.

Most China-based alternatives haven’t yet been established.

Huawei has yet to respond to questions about the impact of the latest sanctions.

The Trump administration says Huawei is a security risk, which the company denies, and is trying to persuade European and other allies to shun its technology for next-generation telecom networks.

Chinese officials accuse Washington of raising phony security concerns to hurt a rising competitor to American tech companies.

The potential impact extends far beyond Huawei. The company spends tens of billions of dollars a year on components and technology from US and other suppliers, purchases that might be disrupted if output of smartphones and other products is blocked.

US suppliers already have complained to Washington that restrictions imposed last May on Huawei’s access to American components and other technology will cost them billions of dollars in lost potential sales.

The curbs announced Friday are the third round of sanctions aimed at cutting off Huawei’s access to US technology and markets.

The company’s American market evaporated after a congressional panel in 2012 labelled Huawei and its Chinese competitor ZTE Corp. security risks and told phone carriers to avoid them.

Last year’s sanctions require US companies to obtain government permission to sell chips and other technology to Huawei.

The company can keep using Google’s Android operating system on its smartphones but lost the ability to preinstall music, maps and other Google services customers expect on phones.

Huawei has launched its own smartphone operating system and is paying developers to create apps to run on it. But the company says sales have suffered.

Despite that, Huawei reported a 2019 profit of 62.7 billion yuan (USD 8.8 billion) and said total sales rose 19% over a year earlier.

The sanctions highlight Huawei’s reliance on technology suppliers despite having one of the world’s biggest corporate research and development budgets.

Huawei has its own semiconductor unit, HiSilicon, but needs manufacturers including TSMC to make the most advanced chips.

Beijing has spent the past two decades and billions of dollars to create a Chinese semiconductor industry. But its biggest producer, SMIC, can only make chips that are two generations behind TSMC.

Huawei had already begun to shift some production from TSMC to SMIC, although SMIC cannot yet produce Huawei’s latest Kirin 980 chipset, said Neil Thomas, a research associate at US think tank Paulson Institute.

But SMIC can probably manufacture earlier-generation Huawei chipsets.

Then-chairman Eric Xu warned in March that more US pressure on Huawei might provoke Chinese retaliation that could disrupt its global industry.

Beijing will not just stand by and watch Huawei be slaughtered, Xu said. “The impact on the global industry would be astonishing.