Bayern Munich defender Mats Hummels will miss the UEFA Champions League encounter against Real Madrid, the German giants announced in a statement.
The 28-year-old defender had to interrupt Bayern's training session on Sunday after suffering an ankle injury, reports Xinhua news agency.
Hummels sustained a distortion of the right upper ankle and also an injury of the capsule apparatus, the club said in a statement on Sunday.
"Very sad about missing at least the next two games," Hummels said in a short statement.
Hummels will thus be not available for the upcoming quarter-final clash against Real Mardid on Wednesday and the Bundesliga match against Bayer Leverkusen on Saturday.
Bayern Munich sit currently atop the Bundesliga standings with a ten-point advantage.
They still have the chance to lift three titles this season as they are in the race for the Bundesliga title, German Cup and UEFA Champions League trophy.